Nitrofurantoin Compares Favorably to Recommended Agents as Empirical Treatment of Uncomplicated Urinary Tract Infections in a Decision and Cost Analysis

Empirical therapy for uncomplicated urinary tract infections in an era of increasing antimicrobial resistance: a decision and cost analysis.

Infectious Diseases Society of America guidelines state that uncomplicated urinary tract infections (UTIs) should be treated empirically with trimethoprim-sulfamethoxazole (TMP-SMZ), unless the community resistance among uropathogens exceeds 10%-20%, in which case a fluoroquinolone (FQ) should be used. However, the data to support this threshold are limited. We performed a cost-minimization and...

Uncomplicated urinary tract infections.

BACKGROUND Urinary tract infections (UTIs) are among the most common types of bacterial infection in outpatient medicine. Rising rates of antibiotic resistance and a better understanding of the ecological adverse effects (collateral damage) of antibiotics warrant a reevaluation of the treatment recommendations for uncomplicated UTI. The new S3 guideline contains updated recommendations. METHO...

Cost-Effectiveness Analysis of Fosfomycin for Treatment of Uncomplicated Urinary Tract Infections in Ontario

Background and Objective. Bacterial resistance to antibiotics traditionally used to treat uncomplicated urinary tract infections (uUTIs) is rising in Canada. We compared the cost-per-patient in Ontario of including fosfomycin (an antibiotic with a low resistance profile) as an option for first-line empirical treatment of uUTIs with current cost of treatment with sulfonamides, fluoroquinolones, ...

A Review of Uncomplicated Urinary Tract Infections

ETIOLOGIC AGENTS AND DRUG SENSITI VITY IN URINARY TRACT INFECTIONS: A SURVEY OF 786 URINE CULTURES

In this survey, 786 urine cultures were studied retrospectively at Shaheed Dr. Rahnamoon Hospital in Tehran. The study showed that E. coli is the most common causative agent of urinary tract infections in both sexes, being responsible for 72% of all cases. Other etiologic microorganisms, in order of frequency, were Staphylococcus, Proteus, Klebsiella, Enterobacter and diphteroids. Approxima...